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“Aim: Retained placenta is an important cause of maternal mortality. The present study was aimed to determine the efficacy of umbilical injection of oxytocin as a treatment modality in this condition. Material and Methods: This was a single-center randomized controlled trial incorporating 58 women with retained placenta of more than 30 min, equally distributed into two study arms

buy PF-6463922 of intra-umbilical injection of oxytocin (50 IU oxytocin diluted with normal saline [NS] to a total volume 30 mL) and intra-umbilical injection of NS (30 mL). Primary outcome was expulsion of the placenta within 30 min following intervention. All the data were analyzed on an intention-to-treat basis. Results: The success rate in the intra-umbilical oxytocin group was 51.72% compared to 20.69% in the control arm. This difference in the primary outcome was statistically significant with a P-value < 0.05 (P =

0.014) favoring intra-umbilical oxytocin infusion with an efficacy rate of 1.5 and a number-needed-to-treat of 3. The peripartum bleeding complications were more in the NS group with a statistically higher (P < 0.001) requirement of extra oxytocin to control post-partum bleeding. There were no differences between the two groups in respect to other secondary outcomes, such as post-partum fever, antibiotic requirement and hospital stay. Conclusion: Umbilical vein injection of 50 IU oxytocin in 30 mL of NS delivered effectively via the see more umbilical cord with milking in cases of retained placenta seems a simple and promising technique to reduce the incidence of a potentially morbid procedure and other complications.”
“Contamination in coastal zones is an increasing problem that adversely affects biological diversity and the functioning of coastal ecosystems. Sediment is an important

compartment of these zones since large quantities of diverse contaminants DAPT cost can accumulate there. Whole-sediment toxicity assays are of increasing importance, and several assay methods using mainly invertebrates have been developed. However, an important part of the benthic community, the microphytobenthos (represented principally by benthic diatoms and cyanobacteria), has surprisingly been neglected. Recently, comprehensive studies have been conducted using benthic marine microalgae with the object of establishing a toxicity assay method for sediment samples. The main results published to date in the literature and obtained by our own team have been compiled and are discussed in this review. The value and feasibility of using certain organisms of the microphytobenthos group in ecotoxicology studies are also discussed, and a sediment quality guideline based on multivariate procedure has been derived from data obtained in previous studies. Finally, future perspectives for research in this field are discussed. (C) 2010 Elsevier Ltd. All rights reserved.”
“Aim: Prenatal exposure to dioxins may result in many adverse health effects.