Given the decreased morbidity of subsequent loop ileostomy takedown compared with a Hartmann’s reversal, this procedure should be given consideration in the management of acute, perforated diverticulitis but may not be warranted in cases of feculent peritonitis. (J Trauma. 2012; 72: 807-814. Copyright (C) 2012 by Lippincott Williams & Wilkins)”
“Objective: To evaluate the morphological effects of phenobarbital treatment on new bone formation and on bone marrow biomechanics
in Wistar rats. Methods: We used ten rats that were divided into two groups: control (CT) and phenobarbital (FE). The FE group received daily doses of phenobarbital 0.035 ml / kg intramuscularly for 60 days. The CT group received the same dose and route of administration of 0.9% saline solution. After 30 days, we introduced a bone see more defect in the parietal bone and implanted porous hydroxyapatite (HAP) in cavities in the tibia. After surgery, we continued the protocols until the end of 60 days when the rats were euthanized, and the bones were collected. Results: The volume of bone formed around HAP in parietal defect and biornechanical findings were lower in animals receiving FE compared to CT. Conclusion: Prolonged use of phenobarbital interferes with bone repair after injury, decreasing the osseointegration of RAP implants and making bones less resistant.”
“Objective: AlcoholEdu for College is a 2- to 3-hour online course for incoming college selleck inhibitor freshmen. This study was the first
multicampus trial to examine effects of AlcoholEdu for College on alcohol-related problems among freshmen. Method: Thirty universities participated in the study. Fifteen were randomly assigned to receive AlcoholEdu,
and the other 15 were assigned to the control condition. AlcoholEdu was implemented by intervention schools during the summer and/or fall semester. Cross-sectional surveys of freshmen were conducted at each university beginning before the intervention in spring 2008/2009; post-intervention surveys were administered in fall 2008/2009 and spring 2009/2010. The surveys included questions about the past-30-day frequency Tariquidar cost of 28 alcohol-related problems, from which we created indices for the total number of problems and problems in seven domains: physiological, academic, social, driving under the influence/riding with drinking drivers, aggression, sexual risk taking, and victimization. Multilevel Poisson regression analyses were conducted to examine intent-to-treat and dosage effects of AlcoholEdu for College on these outcomes. Results: Multilevel intent-to-treat analyses indicated significant reductions in the risk for past-30-day alcohol problems in general and problems in the physiological, social, and victimization domains during the fall semester immediately after completion of the course. However, these effects did not persist in the spring semester. Additional analyses suggested stronger AlcoholEdu effects on these outcomes at colleges with higher rates of student course completion.