Infect Immun 2007, 75:4817–4825.PubMedCrossRef 40. Wang G, van Dam AP, Spanjaard L, Dankert J: Molecular typing of Borrelia burgdorferi sensu lato by randomly amplified polymorphic LY294002 DNA fingerprinting analysis. J Clin Microbiol 1998, 36:768–776.PubMed 41. Busch U, Hizo-Teufel C, Boehmer R, Fingerle V, Nitschko H, Wilske B, et al.: Three species of Borrelia burgdorferi

sensu lato (B. burgdorferi sensu stricto, B afzelii, and B. garinii) identified from cerebrospinal fluid isolates by pulsed-field gel electrophoresis and PCR. J Clin Microbiol 1996, 34:1072–1078.PubMed 42. Brooks CS, Vuppala SR, Jett AM, Alitalo A, Meri S, Akins DR: Complement regulator-acquiring surface protein 1 imparts resistance to human serum in Borrelia burgdorferi. J Immunol 2005, 175:3299–3308.PubMed 43. Kenedy MR, selleck kinase inhibitor Vuppala SR, Siegel C, Kraiczy P, Akins DR: CspA-mediated binding of human factor H inhibits complement deposition and confers serum resistance in Borrelia burgdorferi. Infect Immun 2009, 77:2773–2782.PubMedCrossRef 44. Oliver MA, Rojo JM, Rodriguez de CS, Alberti S: Binding of complement regulatory proteins to group A Streptococcus. Vaccine 2008,26(Suppl 8):I75-I78.PubMedCrossRef 45. Ngampasutadol J, Ram S, Gulati S, Agarwal S, Li C, Visintin A, et al.: Human factor H interacts selectively with Neisseria gonorrhoeae and results in species-specific complement evasion. J Immunol

2008, 180:3426–3435.PubMed 46. Beernink PT, Caugant DA, Welsch JA, Koeberling O, Granoff DM: Meningococcal factor H-binding protein variants expressed by epidemic capsular group A, W-135, and X strains from Africa. J Infect Dis 2009, 199:1360–1368.PubMedCrossRef 47. Oppermann M, Manuelian T, Jozsi M, Brandt E, Jokiranta mafosfamide TS, Heinen S, et al.:

The C-terminus of complement regulator Factor H mediates target recognition: evidence for a compact conformation of the native protein. Clin Exp Immunol 2006, 144:342–352.PubMedCrossRef 48. Hellwage J, Meri T, Heikkila T, Alitalo A, Panelius J, Lahdenne P, et al.: The complement regulator factor H binds to the surface protein OspE of Borrelia burgdorferi. J Biol Chem 2001, 276:8427–8435.PubMedCrossRef 49. Stevenson B, von Lackum K, Riley SP, Cooley AE, Woodman ME, Bykowski T: Evolving models of Lyme disease spirochete gene regulation. Wien Klin Wochenschr 2006, 118:643–652.PubMedCrossRef 50. Rossmann E, Kitiratschky V, Hofmann H, Kraiczy P, Simon MM, Wallich R: Borrelia burgdorferi complement regulator-acquiring surface protein 1 of the Lyme disease spirochetes is expressed in humans and induces antibody responses restricted to CHIR98014 nondenatured structural determinants. Infect Immun 2006, 74:7024–7028.PubMedCrossRef 51. Lederer S, Brenner C, Stehle T, Gern L, Wallich R, Simon MM: Quantitative analysis of Borrelia burgdorferi gene expression in naturally (tick) infected mouse strains. Med Microbiol Immunol 2005, 194:81–90.PubMedCrossRef 52.