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“Neuronal avalanches are a form of spontaneous activity widely observed in cortical slices and other types of nervous tissue, both in vivo and in vitro. They are characterized by irregular, isolated population bursts when many neurons fire together, where the number of spikes per burst obeys a power law distribution. We simulate, using the Gillespie algorithm, a model of neuronal avalanches based on

stochastic single neurons. The network consists of excitatory and inhibitory neurons, first with all-to-all connectivity and later with random sparse connectivity. Analyzing our model using the system size expansion, we show that the model obeys the standard Wilson-Cowan equations for large network sizes (> 10(5) neurons). When excitation and inhibition are closely balanced, networks of thousands of neurons exhibit PFTα research buy irregular synchronous activity, including the characteristic power law distribution of avalanche size. We show that these avalanches are due to the balanced network having weakly stable functionally feedforward dynamics, which amplifies some small fluctuations

into the large population bursts. Balanced networks are thought to underlie a variety of observed network behaviours and have useful computational properties, such as responding quickly to changes in input. Thus, the appearance of avalanches in such functionally feedforward networks indicates that avalanches may be Napabucasin nmr a simple consequence of a widely present network structure, when neuron dynamics are noisy. An important implication is that a network need not be “”critical” for the production of avalanches, so experimentally observed power laws in burst size may be

a signature of noisy functionally feedforward structure rather than of, for example, self-organized criticality.”
“The soft magnetic FeCoAlO thin films with different response at high frequency were prepared by using RF magnetron sputtering. Two different configurations of the sputtering targets were used: the Al(2)O(3) chips were placed on Fe(70)Co(30) disk either uniformly dispersed on the sputtering A-1210477 solubility dmso area (Target-A) or dispersed on the half side of the sputtering area (Target-B). It was found that, although, the films deposited from both of Target A and B possessed good soft magnetic properties and in-plane uniaxial magnetic anisotropy, they showed different behaviors at high frequency. The films deposited by using Target-A have mean permeability of 500 and a cut-off frequency (f(r)) of around 780 MHz, while the films deposited by using Target-B have mean permeability of 200 and a f(r) of 3.4 GHz. The higher f(r) of the later corresponds to the higher uniaxial anisotropic field in the films deposited by using the Target-B, which due to an extra anisotropy induced by the stress resulted from gradient of the Al-O composition. By adjusting the configuration of Target-B, the permeability & f(r) can be tuned to satisfy the different requirements for certain industrial applications.