The mean LV end-diastolic volume, end-systolic volume, and ejection fraction were 93 mL +/- 8, 46 mL +/- 4, and 50% +/- 3, respectively, on multidetector CT images and 92 mL 6 8, 48 mL +/- 5, and 48% +/- 3, respectively, on MR images (P >= .05). The extent of heterogeneous microinfarct was not significantly different between multidetector CT (6.3% +/- 0.8 of the LV mass), MR imaging (6.6% +/- 0.5 of the LV mass), and TTC
staining selleck products (7.0% +/- 0.6 of the LV mass). First-pass multidetector CT and MR imaging demonstrated significant regional differences ( P,.05) in time to peak between the heterogeneous microinfarct and remote myocardium (17.0 seconds +/- 0.3 and 12.4 seconds +/- 0.6, respectively, for multidetector CT and 17.2 seconds +/- 0.8 and 12.5 seconds +/- 1.0, respectively, for MR imaging).
Conclusion: Modern multidetector CT and MR imaging are sensitive modalities with which to depict heterogeneous microinfarcts and determine regional LV dysfunction and decreased perfusion in the territory of intervention. (C) RSNA, 2010″
“Objectives: Seasonal variations in ultraviolet B (UVB) radiation cause seasonal variations
in vitamin D status. This may influence immune responses and play a role in the seasonality of influenza.
Methods: Pandemic and non-pandemic influenzas in Sweden, Norway, the USA, Singapore, and Japan were studied. Weekly/monthly BEZ235 influenza incidence and death rates were evaluated in view of monthly UVB fluences.
Results: Non-pandemic influenzas mostly occur in the winter season in temperate regions. UVB calculations show that at high latitudes very little, if selleck inhibitor any, vitamin D is produced in the skin during the winter. Even at 26 degrees N (Okinawa) there is about four times more UVB during the summer than during
the winter. In tropical regions there are two minor peaks in vitamin D photosynthesis, and practically no seasonality of influenza. Pandemics may start with a wave in an arbitrary season, while secondary waves often occur the following winter. Thus, it appears that a low vitamin D status may play a significant role in most influenzas.
Conclusions: In temperate latitudes even pandemic influenzas often show a clear seasonality. The data support the hypothesis that high fluences of UVB radiation (vitamin D level), as occur in the summer, act in a protective manner with respect to influenza. (C) 2010 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.”
“Purpose: To prospectively evaluate magnetic resonance ( MR) signal abnormalities and the time course of T1 and T2 values in a rabbit model of acute nerve traction injury with histologic and functional recovery correlation.
Materials and Methods: All experimental protocols were approved by the institutional animal use and care committee. Acute traction injury was produced in the sciatic nerve of one hind limb in each of 28 rabbits.