The patient was successfully treated with a bypass procedure and combined anticoagulation. It seems that platelet receptor polymorphisms are a moderate risk factor for local artery thrombosis regardless of vascular region. The obligatory precondition is pre-existing vascular damage, such as that caused by a local compression syndrome. (J Vasc Surg 2008;48:1335-7.)”
“Segmental arterial mediolysis (SAM) is a rare condition characterized by splanchnic
arterial catastrophe caused by mediolysis. We report a 59-year-old man with a ruptured splenic arterial aneurysm who was successfully treated by coil embolization. He underwent additional resection of large gastroepiploic and residual splenic aneurysms. Pathological examination LXH254 showed mediolysis and tearing, compatible with SAM. Furthermore, lie developed acute dissection of the superior mesenteric artery (SMA) one and a half years later, demonstrated by computed tomography. This report demonstrates that SAM is characterized by multiple lesions of the splanchnic arteries at different times, and requires treatment suited to the lesions, including careful
long-term observation. (J Vase Surg 2008;48:1338-41.)”
“Cadherin-6(Cdh6) is a type 11 classic cadherin cell adhesion molecule whose expression delineates specific sets of rhombomeres during early mouse development. Here we establish a stable BAC transgenic mouse line in which enhanced MM-102 supplier green fluorescent GW4064 concentration protein (EGFP) recapitulates Cdh6 expression within the embryonic hindbrain. When the transgenic posterior hindbrain region at the embryonic (E) day 8.75-E9.75 that contains EGFP-positive rhombomere (r) 6-7 and EGFP-negative r4-5 cells was dissociated to single cells and incubated in suspensions, they were found to make aggregates only in the presence of calcium ion with the EGFP-Cdh6-positive/negative populations segregating each other in an aggregate.
We further demonstrated that EGFP-Cdh6 expression boundary in the transgenic hindbrain at E9.5 shifted rostrally by the treatment that allows Hox gene expression anteriorize in the whole embryo Culture system. These results suggest the role of Cdh6 in coordinating mouse hindbrain compartments possibly under the control of Hox gene regulatory network. (C) 2008 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.”
“Objective: Traumatic thoracic aortic injuries are associated with high mortality and morbidity. These patients often have multiple injuries, and delayed aortic repair is frequently used. Endoluminal grafts offer an alternative to open surgical repair. We performed a meta-analysis of comparative studies evaluating endovascular vs open repair of these injuries.
Methods.