The study design was a randomized clinical trial conducted on 51 elderly women (> 60 years) with UUI. All were treated
with 12 weeks of bladder retraining and pelvic floor muscle exercises, and 25 were randomly selected to receive TTNS in addition to the standard therapy. The cases were evaluated at the baseline and after the end of therapy by 3-day bladder diary, quality of life questionnaires (QoL), and subjective response.
Of the patients, 68.0% in TTNS group reported cure or improvement vs. 34.6% in the control group (P = 0.017). TTNS showed significant improvement in most areas of QoL and in UUI parameters when compared with the control group.
TTNS is efficacious to treat UUI in older women.”
“Background: Recent research suggests that central pulse pressure may be a better indicator of cardiovascular disease outcomes than brachial pressure. Little information is available regarding the effect of food intake on postprandial selleck chemicals central pressure and other measures of arterial stiffness when measured with a noninvasive signaling pathway pulse wave analysis (PWA) technique.
Objective: The objective was to investigate the effects of water and food plus water intake on brachial and central blood pressure (BP) and measures of arterial stiffness,
including augmentation pressure and augmentation index, by using the PWA technique.
Design: Measurements of BP and PWA were made at fasting and for 2 h after the intake of water or breakfast (1300 kJ) in random order in 35 subjects.
Results: Roscovitine solubility dmso Baseline fasting measures of BP and arterial stiffness were not significantly different before the 2 interventions. Consumption of food plus water, compared with water alone, led to a significantly lower (all P < 0.01) brachial diastolic pressure (difference: -3.8 mm Hg), central BP(difference: systolic, -6.1 mm Hg; diastolic, -3.8 mm Hg), central pulse pressure (difference: -2.4 mm Hg), mean arterial pressure (difference: -4.6 mm Hg), augmentation pressure (difference: -2.9 mm Hg), and augmentation index (difference: -5.3 mm Hg).
Conclusions: Markers of central hemodynamics are sensitive to feeding
state and therefore should be measured at fasting to avoid variability due to recent (within 2-3 h) food intake. This is especially important when measurements are repeated over time to assess the effect of medication or lifestyle changes on cardiovascular disease risk factors. Am J Clin Nutr 2009;90:298-303.”
“The piezoresistant effect in conducting fiber-filled composites has been studied by a continuum percolation model. Simulation was performed by a Monte Carlo method that took into account both the deformation-induced fiber bending and rotation. The percolation threshold was found to rise with the compression strain, which explains the observed positive piezoresistive coefficients in such composites. The simulations unveiled the effect of the microstructure evolution during deformation.