This study demonstrates the suitability of using recombinant proteins to measure anti-RV immune responses and serves as a

“”proof of principle”" to examine the antibody responses generated to other recombinant RV proteins and thereby possibly identify a correlate of protection. (C) 2012 Elsevier B.V. All rights reserved.”
“Individuals of all ages extract structure from the sequences of patterns they encounter in their environment, an ability that is at the very heart of cognition. Exactly what underlies this ability has been the subject Angiogenesis inhibitor of much debate over the years. A novel mechanism, implicit chunk recognition (ICR), is proposed for sequence segmentation and chunk extraction. The mechanism relies on the recognition of previously encountered subsequences (chunks) in the input rather than on the prediction of upcoming items

in the input sequence. A connectionist autoassociator model of ICR, truncated recursive autoassociative chunk extractor (TRACX), is presented Pitavastatin order in which chunks are extracted by means of truncated recursion. The performance and robustness of the model is demonstrated in a series of 9 simulations of empirical data, covering a wide range of phenomena from the infant statistical learning and adult implicit learning literatures, as well as 2 simulations demonstrating the model’s ability to generalize to new input and to develop internal representations whose structure reflects that of the items else in the input sequence. TRACX outperforms PARSER (Perruchet & Vintner, 1998) and the simple recurrent network (SRN, Cleeremans & McClelland, 1991) in matching human sequence segmentation on existing data. A new study is presented exploring 8-month-olds’ use of backward transitional probabilities to segment auditory sequences.”
“The development of next-generation sequencing technologies has facilitated the study

of HIV drug resistance evolution. However, the high capacity and per-run cost of many sequencers is not ideal for viral sequencing unless many samples are analyzed simultaneously. Ion semiconductor sequencing has recently emerged as a flexible, lower-cost alternative with short runtime. This paper describes the use of Ion Torrent devices for deep sequencing of drug resistant HIV samples. High levels of sequencing coverage were obtained in HIV Gag and protease, allowing the detection of mutations at low frequencies. (C) 2013 Elsevier B.V. All rights reserved.”
“Loss of previously established behaviors in early childhood constitutes a markedly atypical developmental trajectory. It is found almost uniquely in autism and its cause is currently unknown (Baird et al., 2008).