Treatment for both groups was administered by local infiltration, and pain scores were recorded at various intervals. Primary outcomes were pain scores recorded 4-24 h postoperation. Secondary outcomes included time to the first ERK screening administration of analgesic and total consumption of analgesics for all children, time to first water request, first oral intake, incidence of nausea or vomiting, and time to discharge.
Results: From postoperative hours 4-24, children in
the RD group had lower pain scores than children in the R group (P < 0.05). Total fentanyl consumption was significantly decreased in the RD group compared to the R group (50.9 +/- 9.3 vs. 103.9 +/- 11.5 mu g, P < 0.001). The time to first water request and first oral intake were significantly shorter in the RD group [(40 min (27-64) vs. 64 min (43-89); P < 0.001) and (54 min (40-91) vs. 85 min (67-127); P < 0.001), respectively]. Oral intake was significantly improved, and the incidence of nausea and vomiting were reduced in the RD group (P < 0.05). The time to discharge was shorter this website in the RD group when compared with the R group (9.06 +/- 0.89 d vs. 7.05 +/- 0.71 d; P < 0.001).
Conclusions: Ropivacaine plus dexamethasone infiltration effectively lowers pain, improves oral intake, lowers postoperative nausea and vomiting, and decreases the time to discharge. (C) 2013 Elsevier Ireland Ltd. All rights reserved.”
“Background. Fear of recurrence (FOR)
has been increasingly recognised as an issue of significant burden for most cancer patients, and has been associated with psychological morbidity and reduced quality of life. More recently, the impact of recurrence fears has been indicated in the families of cancer patients. However, there has been a lack of prospective research.
Aim: To systematically examine distress and illness concerns among patient-carer dyads.
Methods: A multi-centre prospective study of head and neck cancer patients and their carers (patients, LY2603618 price n = 101; carers, n = 101), surveyed at two time-points following
diagnosis.
Results: Carers recorded higher recurrence concerns on average than the patient group (p < 0.001). A predictive path model of patient and carer self-reports of distress and FORs was explored, with an excellent overall fit of the final model (chi(2) = 15.4, df = 12, p = 0.22, Comparative Fit Index (CFI) = 0.994, Root Mean Square Estimate of Approximation (RMSEA) = 0.053).
Conclusions: The preliminary results establish that early fears and distress within individuals govern later reports on these same attributes, but that there is some weak evidence of influence from one attribute to another within and across individuals in the dyad. Future prospective dyadic research is warranted to ascertain the level of these fears over an extended time and their relationship to patient and carer adaptation. Intervention may be needed to reduce this disease concern to a manageable level at an early stage of the illness trajectory.