The average number of YPLL per death was approximately 15 for melanoma and 10 for NMSC. We found the costs attributable to melanoma and NMSC ranged from SUS39.2 million to $US28.9 million for morbidity and

$US3.3 billion to $US1.0 billion for mortality, respectively.

It is clear from the published literature that skin cancer leads to significant YPLL and indirect costs associated with premature mortality and morbidity. Prevention and early detection efforts are important in helping reduce the incidence of melanoma and NMSC, and the related deaths and productivity losses.”
“The halogen-free flame retardant (HFFR) ethylene-vinyl acetate copolymer (EVM)/ATH/SiO2 composites have been prepared by melting compounding method, learn more and the flame retardant, thermal stability, rheological, electrical, and mechanical properties have been investigated by cone calorimeter, LOI, UL-94, TG, FE-SEM, rotational rheometer, dielectric breakdown, and ultimate tensile. The results indicate that the flame retardant of EVM vulcanizates is improved and the fire jeopardizing is dramatically reduced due to the addition of ATH. It is necessary that sufficient loading of ATH (>= 120 phr) is needed to reach essential level (LOI > 30; V-0 rating) of flame retardant for HFFR EVM/ATH/SiO2 composites used as cable in industry. The rheological

characteristics show that at all the measurement this website Sotrastaurin research buy frequencies, the storage and loss modulus of the composites increase monotonously as the concentration of ATH filler increases, while the complex viscosity and tan delta present reverse trend. And also, it has been found that the HFFR composites at high filler concentrations still keep good mechanical and electrical properties, which is very important for practical applications as cable. (C) 2010 Wiley Periodicals, Inc. J Appl Polym Sci 120: 368-378, 2011″
“Bovine serum albumin-loaded beads were prepared by ionotropic gelation of alginate with calcium chloride and chitosan. The effect of sodium alginate concentration and chitosan concentration on the particle size and loading efficacy was studied. The diameter

of the beads formed is dependent on the size of the needle used. The optimum condition for preparation alginate-chitosan beads was alginate concentration of 3% and chitosan concentration of 0.25% at pH 5. The resulting bead formulation had a loading efficacy of 98.5% and average size of 1,501 mu m, and scanning electron microscopy images showed spherical and smooth particles. Chitosan concentration significantly influenced particle size and encapsulation efficiency of chitosan-alginate beads (p<0.05). Decreasing the alginate concentration resulted in an increased release of albumin in acidic media. The rapid dissolution of chitosan-alginate matrices in the higher pH resulted in burst release of protein drug.

Surface trapping state was proved to be the origin of the long lifetime component by comparing fresh and eight months aged quantum dot. It was observed that the excitonic state lifetime of the quantum dots was reduced by nonradiative resonant energy transfer to gold nanofilm. Nonradiative resonant energy transfer Selleck Torin 2 time, which was comparable with the surface trapping time, was calculated based on the data of picosecond photoluminescence

measurements. No nonradiative energy transfer from surface trapping state to gold nanofilm, thus the lifetime of surface trapping state was not affected obviously. It is suggested that in the assembly combined with quantum dot and gold nanostructure, nonradiative energy transfer will occur after the population of excitonic state, and compete with surface trapping process. The interactions between surface trapping state and gold nanoflim were not exhibited. (C) 2010 American Institute of Physics. [doi: 10.1063/1.3503518]“
“Polyaniline nanoparticles have been synthesized through simple micelle technique and then grafted it with silanized silica gel to develop a novel hybrid material. The nanoparticles are characterized by UV-Vis, TEM, CV, SEM, TGA, DTG, and DSC. Silanization

and grafting reactions are evaluated by FTIR and chemical test. The Cr(VI) binding behavior of the composite is studied in various pH of the medium, and both competitive and noncompetitive conditions. The particle size, adsorption capacity, and surface area of the material are found to be 100 nm, 135 mg/g, and 720 m(2)/g, respectively. (C) 2010 Wiley Periodicals, Inc. J Appl Polym Sci 119: 823-829, 2011″
“Laser plasma plumes buy RG-7388 see more were generated in aluminum

rectangular cavities of fixed depth (6 mm) and varying height (2.0, 1.5, and 1.0 mm). Space and time resolved visible emission spectroscopy, gated intensified visible imaging, and Langmuir probe diagnostics were utilized to diagnose the evolution of the confined plasma plumes in comparison to freely expanding plasma plume generated from ablation of a planar target. The constrained plasma behavior displayed a multiphase history. Early stage interactions (t<100 ns) resulted in enhanced continuum and line emission, shockwave formation and plasma plume rebound. Later phase, long duration plasma-surface interactions (t>160 ns) resulted in sustained “”decay,”" i.e., a rapid termination of continuum emission, in concert with decreases in peak electron density (N(e)) and plasma temperature (T). This later phase originates from loss mechanisms which bleed the plasma plume of thermal energy and charged particles. These loss mechanisms increase in magnitude as the duration of the plasma-surface interaction increases. The transition from enhancement phase, originating from hydrodynamic containment, and plasma-surface collisions, to decay phase is described and occurs for each cavity at a different point in the space time history.

Important nonmolecular techniques that are used in conjunction with molecular methods are also highlighted.”
“The efficiency of the extraction of fresh and dried leaves of Piper piscatorum was evaluated

employing supercritical CO2 and co-solvents (10% ethanol and 10% methanol) at 40 degrees C and 70 degrees C and a pressure of 400 bar. The extracts were characterized chemically by GC-MS and GC-FID. The major components find more of the extracts were piperovatine, followed by palmitic acid, pentadecane and pipercallosidine. Drying of the leaves caused modifications in their composition, mainly reducing the concentration of the amides, which have activity as anesthetics. The highest yields of the piperovatine (0.93%, w/w) and pipercallosidine (0.24%, w/w) were obtained from the fresh leaves extracted with CO2 modified with 10% ethanol at 40 degrees C. (C) 2012 Elsevier B.V. All rights reserved.”
“Purpose of review

Active surveillance has evolved to become a standard of care for favorable-risk prostate cancer. This article is a summary of the rationale, method, and results of active surveillance beginning in 1995 with the first prospective trial of this approach.

Recent findings

This was

a prospective, single arm cohort study. Patients were managed with an initial expectant approach. Definitive intervention was offered to those patients with a prostate specific antigen (PSA) doubling time of less than 3 years, Gleason score progression (to 4 + 3 or greater), or unequivocal clinical progression. Since November 1995, 450 patients have been managed with active surveillance. https://www.selleckchem.com/products/elacridar-gf120918.html Median follow-up is 6.8 years (range 1-16 years). Overall survival is 78.6%. Ten-year prostate cancer

actuarial survival is 97.2%. Five of 450 patients (1.1%) have died of prostate cancer. Thirty percent of patients have been reclassified as FK506 concentration higher risk and offered definitive therapy. The commonest indication for treatment was a PSA doubling time less than 3 years (48%) or Gleason upgrading (26%). Of 117 patients treated radically, the PSA failure rate was 50%. This represents 13% of the total cohort. Most PSA failures occurred early; at 2 years, 44% of the treated patients had PSA failure. The hazard ratio for nonprostate cancer to prostate cancer mortality was 18.6 at 10 years.

Summary

We observed a very low rate of prostate cancer mortality in an intermediate time frame. Among the one-third of patients who were reclassified as higher risk and retreated, PSA failure was relatively common. However, other cause mortality accounted for almost all of the deaths. Further studies are warranted to improve the identification of patients who harbor more aggressive disease in spite of favorable clinical parameters at diagnosis.”
“Background: Studies from the United States report a large increase in the surgical treatment of distal radius fractures with open reduction and internal fixation using locked plates.

Information on socio-demographic characteristics, risk Selleck 3-Methyladenine factors and blood pressure measures was collected using standardized protocols. Prevalence of HTN and pre-HTN were 22 and 44%, respectively. Older age (P<0.001), higher body mass index (BMI) (P = 0.07), television ownership (P = 0.01) and less work-related vigorous physical activity (P = 0.02) were associated with higher prevalence of HTN and higher blood pressure measures (all P<0.05). Frequent

meat and fat intake were associated with higher HTN prevalence (trend P = 0.02 and 0.07, respectively). Frequent fruit and vegetable intake was significantly associated with lower blood pressure measures (all P<0.05). HTN and pre-HTN are common in rural SSA. Modifiable risk factors (such as BMI, dietary intake and physical activity) are associated with HTN prevalence in this population, indicating potential opportunities for prevention measures. Journal of Human Hypertension (2010)

24, 786-795; doi:10.1038/jhh.2010.14; published online 11 March 2010″
“Background: A minority of HIV/HCV coinfected patients with opiate addiction undergo HCV treatment. HCV therapy for HCV-monoinfected methadone maintenance (MM) recipients is safe and effective. We evaluated treatment efficacy and adherence Napabucasin ic50 to pegylated interferon (pegIFN) among HIV/HCV coinfected MM recipients.

Methods: HCV treatment-naive, HIV-infected persons 18-65 years with chronic HCV genotype 1 on MM were prospectively enrolled in an HCV treatment study at two HIV clinics. At weekly visits pegIFN alfa-2a injections were directly administered. Daily MM recipients had morning ribavirin delivered with methadone at off-site methadone clinics. Weekly take-home MM recipients took ribavirin unsupervised. Target enrollment was 30 participants.

Results:

During 18 recruitment months, 11 participants were enrolled, RSL-3 6 of whom received daily methadone. Mean age was 46, 64% were female, 5 were Caucasian, 4 Black and 2 Hispanic. At baseline, 82% had high HCV RNA and 55% had stage 2 fibrosis or greater. The majority (91%) were on HAART, and 82% had undetectable HIV RNA with a median CD4(+) of 508 Cells/mu L. All had polysubstance use history, non-substance-based psychiatric diagnoses and were on psychotropic medications pre-enrollment. Two (18%) participants achieved a Sustained Virologic Response (SVR).

Two completed 48 treatment weeks, 5 were withdrawn due to adverse events, 2 dropped out prematurely and 2 had treatment discontinued for virologic non-response. Of on-treatment weeks, adherence to pegIFN was >99%. Conclusions: SVR rate was comparable to historic controls for coinfected genotype 1 patients, with optimal pegIFN adherence. Adverse effects often prevented therapy completion in this population. (C) 2010 Elsevier Ireland Ltd. All rights reserved.

Cyst growth in ADPKD involves fluid accumulation within the cyst lumen driven by cystic fibrosis transmembrane conductance regulator (CFTR)-mediated transepithelial Cl(-) secretion. This suggests that inhibitors of the CFTR Cl(-) channel might retard cyst growth. This review considers how knowledge of CFTR structure and function Selleck KPT-8602 and its role in transepithelial salt and water movements provides insight into the mechanism of action of CFTR inhibitors. Some small molecules,

termed open-channel blockers, inhibit directly the CFTR Cl(-) channel by physically obstructing the CFTR pore and preventing Cl(-) flow. By contrast, other small molecules, termed allosteric inhibitors, bind to CFTR at a site remote from the channel pore and MK5108 research buy interfere with conformational changes that open the pore. The application of high-throughput screening to CFTR drug discovery has led to the identification of new inhibitors of the CFTR Cl(-) channel including the thiazolidinone CFTR(inh)-172 and the glycine hydrazide GlyH-101. The demonstration that CFTR inhibitors retard cyst expansion and kidney enlargement in mouse models of ADPKD provides proof of concept for the use of small-molecule

CFTR inhibitors in the treatment of ADPKD.”
“This prospective, single-centre cohort study aimed to evaluate plasmin generation and fibrinolysis during and after cardiopulmonary bypass (CPB) surgery in a cohort of children up to 6 years of age. Blood samples were drawn at eight time points: after induction of

anesthesia, before unfractionated heparin (UFH), after UFH, after initiation of bypass, before protamine, after HIF-1�� pathway protamine, after chest closure, and 6 h after chest closure. The study identified an increase in fibrinolysis during CPB and particularly up to 6 h afterward in children. This could be the mechanism for the significant bleeding events observed in this young population after CPB. This study establishes the foundation for future studies in this area, particularly those focusing on clinical outcomes after CPB surgery.”
“Purpose: To investigate the effects of ursolic acid (UA) on expressions of ERK1, C-Jun, C-Myc and Cyclin D1 in Human Umbilical Vein Endothelial Cells (HUVEC), and to explore the mechanism of anticancer activity of UA on glioma.

Methods: HUVEC was treated with UA (0, 31.5, 62.5, 125, 250, 500 mu g/mL) for 24 h, and 125 mu g/mL for 0, 12, 24, 48 h, respectively) and PD98059 in vitro. Real-time polymerase chain reaction (RT-PCR) was performed to measure the endogenous mRNA levels of ERK1, C-Jun, C-Myc, and Cyclin D1, and Western blotting was used to determine the expressions of ERK1, C-Jun, C-Myc, and Cyclin D1 proteins.

Results: The results show that the mRNA levels of ERK1, C-Jun, C-Myc, and Cyclin D1 were down-regulated, following treatment with UA (in a dose- and time-dependent manner) and PD98059 (p < 0.05).

The proportion of patients

that displayed positive reaction for estrogen and androgen receptors in epithelial cells of the ovary was evaluated according to menopausal status and associated pathology.

Results: The proportion of patients that displayed a positive receptor expression in the epithelial cells of the ovarian surface and cortical inclusion cysts shows that ER alpha is present in 20 of 79 patients (0.25), AR in 33 of 79 (0.42) and GPR30 in 38 of 55 (0.69). There are no differences in ER alpha, AR, and GPR30 expression between pre and postmenopausal GSK2399872A ic50 patients and considering the associated pathology, proportions for ER alpha and GPR30 are similar. The patients with cervical cancer show a higher proportion of AR expression in epithelial cells of the ovary, which is statistically significant (P < 0.01) compared with patients with other

proliferative diseases.

Conclusions: The presence of ER alpha, AR, and GPR30 in the surface epithelial ovarian cells and its derivatives are observed with a proportion that is specific for each receptor. The proportion of expression for these receptors in the epithelial cells of the ovary does not change after menopause. BAY 73-4506 clinical trial The proportion of ovaries with AR positive epithelial cells in patients with cervical squamous carcinoma is higher compared with other gynecological pathologies.”
“OBJECTIVE: To compare the normal labor progress of women whose labor was induced with that of women who labored spontaneously.

METHODS:

A retrospective cohort study of all consecutive women admitted Selleck Pexidartinib for labor at 37 weeks or more of gestation from 2004-2008 who reached the second stage of labor. Women whose labor was induced and women whose labor was augmented were compared with women who labored spontaneously without augmentation. Results were stratified by parity. Univariable and multivariable analyses were performed; interval censored regression was used to estimate the median time spent to progress 1 cm in dilation and the total time from 4-10 cm dilation by parity.

RESULTS: Of 5,388 women in the cohort, 2,021 spontaneously labored, 1,720 were augmented, and 1,647 were induced. After adjusting for race, obesity, macrosomia, and Bishop score, women who were induced had a significantly longer total time in labor than women who labored spontaneously (median [95th percentile] in hours for nulliparous women: 5.5 [16.8] induced compared with 3.8 [11.8] spontaneous; for multiparous women 4.4 [16.2] induced compared with 2.4 [8.8] spontaneous). However, median time to progress 1 cm dilation in active labor (6 cm or greater) was similar in induced and spontaneous labor. The time to progress 1 cm dilation in latent labor (less than 6 cm) was significantly longer in women who were induced compared with women who experienced spontaneous labor.

Ultimately, the decision is really a litmus test for a Plastic Surgery program. The authors aim to evaluate factors influencing ascent in Plastic Surgery leadership, screening assay including training history, internal promotion, and external recruiting.

Methods: All Plastic Surgery residency programs accredited by the Accreditation Council for Graduate Medical Education were noted (n = 71). Academic departmental chairs or divisional chiefs of these residency programs were identified at the time of study design (October 1, 2011). For each chair or chief, gender, training history, and faculty appointment immediately prior to the current leadership position

was recorded.

Results: There were 71 academic chairs or chiefs of

Plastic Surgery residency programs at the time of data collection. The majority (62%) had done fellowship training following Plastic Surgery residency. Fellowships included hand (43%), craniofacial (29%), microsurgery (18%), and other types (10%). The majority (73%) of leaders were internal hires (P < 0.01), having faculty appointments at their institutions prior to promotion. However, only a fraction (22%) of these internal hires had done Plastic Surgery residency or fellowship training at that institution (P < 0.01). External recruits consisted of 27% of all 71 academic hires (P < 0.01).

Conclusions: Many factors influence the decision to recruit leadership from internally or to hire an external candidate. These include the time https://www.selleckchem.com/products/a-1331852.html to fill the position, program culture, candidate experience, LBH589 purchase and cost. These results support that the insider/outsider hire decision is ultimately one

of duality. That dichotomy is achieved with an emphasis on internal promotion, but always with an eye towards the advantages of bringing in external talent as a valuable contribution to increase organizational success.”
“It is currently thought that memory formation requires the activation of NMDA receptors (NMDARs) in the hippocampus. However, recent studies indicate that these receptors are not necessary for all forms of learning. The current experiments examine this issue using context fear conditioning in mice. First, we show that context fear can be acquired without NMDAR activation in previously trained animals. Mice trained in one environment (context A) are subsequently able to learn about a second environment (context B) in the presence of NMDAR antagonists. Second, we demonstrate that NMDAR-independent learning requires the hippocampus and is dependent on protein synthesis. However, unlike NMDAR-dependent learning, it is not contingent on the expression of activity-regulated cytoskeleton-associated protein (Arc). Lastly, we present data that suggests NMDAR-independent learning is only observed when recently stimulated neurons are reactivated during conditioning.

Materials and Methods This is a retrospective study based on the national AE reporting database and on the regional database system for deliveries. AEs recorded after the delivery of 1 of the 4 types of FFP were pairwise compared, with appropriate statistical corrections. Selisistat datasheet Results 105964 FFP units were delivered (38 center dot 4% Q, 17 center dot 9% SD, 9 center dot 7% MB and 34% AI). Statistical comparisons of AEs identified only a difference in AE rates between quarantine and solventdetergent plasma. Conclusions FFP was confirmed to be extremely safe in general, especially if one considers severe’ AEs. All types of FFP were associated

with extremely low occurrences of AEs. Q, SD, MB and AI led, respectively, to 7 center dot 14, 4 center dot 86, 1 center dot 05 and 4 center dot 16 AEs per 10000 deliveries.”
“Drug-resistant

virus infection has been a major hurdle in the management of human immunodeficiency virus type 1 (HIV-1) infection. Recently, three novel antiretrovirals [raltegravir (RAL), etravirine (ETR), and darunavir (DRV)] were introduced into the market almost simultaneously, and salvage CYT387 manufacturer regimens containing these three antiretrovirals have been reported to exhibit strong potency against drug-resistant HIV-1 infection. However, the sustainability of such regimens remains unclear, particularly for patients infected with multidrug-resistant viruses. Here we report a case of super-multidrug-resistant HIV-1 infection which has been successfully controlled by novel combination therapy including RAL, ETR, and DRV for over 2 years, indicating that the novel combination could become an ultimate weapon against drug-resistant HIV infection

and could alter the landscape of HIV salvage therapy.”
“Objective: To discuss the unusual occurrence of both familial hypocalciuric hypercalcemia (FHH) and primary hyperparathyroidism in the same patient and to explore potential mechanisms of association and issues related to clinical management.

Methods: We discuss the diagnosis, compare the clinical presentations of FHH and MI-503 nmr primary hyperparathyroidism, review the literature regarding patients who have presented with both disorders, and discuss management considerations. We also describe 2 patients who have both FHH. (confirmed by genetic testing for a mutation in the gene encoding the calcium-sensing receptor [CASR] and primary hyperparathyroidism.

Results: The occurrence of both FHH and primary hyperparathyroidism in the same patient has been reported in a few cases, including 2 patients described here, one of whom was documented to have a novel CASR mutation. In those with clinical sequelae of hyperparathyroidism, parathyroidectomy has led to reduction, but not normalization, of serum calcium levels.

“
“P>Diltiazem is a calcium channel antagonist that has been commonly associated with currently used immunosuppressants to prevent acute graft rejection in humans. In this 5-Fluoracil research buy study, we examined the possibility that diltiazem may affect human dendritic cell (DC) functions in response to lipopolysaccharide (LPS) stimulation and may induce the generation of DC with the capacity to generate CD4+ regulatory T cells (Tregs). Blood monocytes were cultured in the presence of diltiazem at the beginning of their differentiation process into DC. Monocyte-derived DCs were stimulated with LPS,

and DCs differentiated in the presence of diltiazem showed a decreased interleukin (IL)-12 production and an enhanced IL-10 production. When cultured

with CD4+CD45RA+ they were able to enhance the CD4+Foxp3+ T-cell population and to induce slowly proliferating T cells, which showed a significant increase of transforming growth factor (TGF)-beta production. These T cells suppress proliferation of activated autologous T cells, and we show that this effect is attributable to soluble factors, CA3 price primarily to TGF-beta. Blockade of TGF-beta by specific monoclonal antibodies reversed this inhibitory effect. Herein, we provide new evidence that diltiazem-conditioned monocyte-derived DC induce T cells which acquire a regulatory phenotype and activity similar to those described for Tregs.”
“Study Design. Cohort study.

Objective. To assess the responsiveness and minimal clinically important change (MCIC) of 6 commonly-used performance tests (5-minute walking, 50-ft walking, sit-to-stand, 1 minute stair climbing, loaded forward reach, Progressive Isoinertial Lifting Evaluation).

Summary of Background Data. Performance tests are used to evaluate physical function in people with low back pain. Little is known about their clinimetric properties.

Methods. Performance tests were buy GS-9973 administered in people with chronic nonspecific low back pain (n = 198) before and after 10 weeks of treatment. At 10 weeks, the global perceived effect scale was used to determine

if participants judged themselves as worsened, unchanged, or improved. The mean change scores for each performance test were calculated. A performance test was considered responsive if the area under the receiver operating characteristic curve (AUC) was equal to or greater than 0.70. We used 2 methods to evaluate MCIC: the optimal cut-off point based on the receiver operating characteristic curve, which takes into account both sensitivity and specificity, and the minimal detectable change for improvement, which considers test specificity only.

Results. In general, the mean change scores were the smallest in participants who judged themselves worsened and largest in those reporting to be improved. Sit-to-stand (AUC = 0.75) and stair climbing (AUC = 0.72) were the only performance tests that showed adequate responsiveness.

The case control group consisted of 40 donors matched with regard to sex, age, BMI and surgical technique. All donors were maintained on standardized multimodal analgesia combining nurse-controlled oxycodone treatment and acetaminophen. CILA donors had lower median cumulative consumption of morphine equivalents (CCME) (7 mg [0-56] vs. 42 mg [15-127]; p < 0.0000001), lower incidence of nausea (18 [45%] vs. 35 [87.5%] donors; p < 0.001), shorter time PU-H71 solubility dmso in postoperative care unit (160 vs. 242.5 min; p < 0.001) and shorter hospital stay (4 [4-7] vs. 6 [4-11] days; p < 0.001). In 32.5% of CILA donors the CCME was 0 mg (0% in matched control group, p < 0.001).

CILA with 0.5% ropivacaine provides effective postoperative pain relief, reduces the need for opioid treatment and promotes postoperative recovery.”
“The underutilized, edible green raw (whole) fruits of amra, Spondias pinnata K. (Anacardiaceae family) from the eastern region of India were investigated for their nutraceutical and therapeutic potential.

A thorough nutritional RSL3 datasheet characterization of this fruit demonstrated it as a source of energy (348 kcal/100 g DM), phenolic compounds, natural antioxidants and minerals. It is also a moderate source of ascorbic acid, malic acid, calcium, phosphorus and other nutrients. The phytochemical screening revealed 5.12 +/- 0.32 mg 100 g(-1) DM of alkaloids followed by saponins and tannins. All assays were carried out in three different solvent extracts of the fruit. Total phenolic, flavonoid and flavonol contents were obtained as 210 +/- 1.89 mg GAE, 28.0 +/- 0.91 mg CE and Selleckchem ABT 737 9.97 +/-

0.72 mg RE respectively in 100 mg mix solvent extract (MSE). Antioxidant activity of different extracts (as DPPH scavenging) ranged from 0.73 to 0.59 mg ml(-1) as IC50 value, ABTS with a trolox equivalent antioxidant concentration (TEAC) value as 0.68 to 0.83 and FRAP 5.97 to 7.93 mg TE 100 mg(-1) extract. LC-MS/MS analysis revealed the presence of gallic acid, salicylic acid, chlorogenic acid, ellagic acid. p-coumaric acid, 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid, quercetin, catechin, myrecetin and rutin. The MSE showed the highest antimicrobial activity (against Listeria monocytogenes (MIC 1.8 mg ml(-1))) and a-amylase inhibition capacity (as IC50: 29.3 mg ml(-1) extract). GC/MS screening showed the presence of vitamin E, furfural, phytosterol, campesterol and fatty acids. Analysis of volatile flavor showed isopropyl myristinate as a major compound followed by the other monoterpenes and sesquiterpenes. The current study explains the nutritional as well as medicinal utility of the fruit which is a rich source of minerals and antioxidants such as phenols and flavonoids. (C) 2011 Elsevier Ltd. All rights reserved.”
“Peripartum acute renal failure is an important complication related to pregnancy leading to significant morbidity and mortality.